PATENTED TECHNOLOGY

Microlyte® Matrix is a one-of-a-kind wound matrix that is fully-synthetic, antimicrobial, and bioresorbable.

The Microlyte Difference

Microlyte® Matrix absorbs wound fluid and forms a soft material that conforms to the wound surface and maintains a moist environment. Microlyte® Matrix is so thin that it inherently conforms to the underlying contours of a moist wound bed, providing intimate contact with the microbes on wound-bed. Antimicrobial silver in Microlyte® Matrix kills bacteria that come into contact with the product and reduces microbial colonization. This action reduces loss of silver in wound exudate and provides effective antimicrobial action at much lower silver concentrations. The dressing contains silver only to prevent or minimize microbial growth within the dressing. Reduction of bacterial bioburden may reduce microbial colonization and risks of wound infection.

Fast and Effective

Microlyte® Matrix is easy to apply. Once removed from its pouch and placed on a moist wound bed, Microlyte® Matrix immediately begins to hydrate and conform to the contours of the wound. Within seconds, the dressing has completely adhered to the wound and can be covered with the secondary dressing preferred for a given wound.

Microlyte® Matrix provides a low, but effective level of silver to the wound bed for at least 3 days to kill bacteria that come in contact with the product. This efficiency translates to less wound staining and lower residual toxicity.

Simply Peel and Place

To reapply, carefully remove the secondary cover dressing. Gently irrigate wound with sterile saline to remove necrotic tissue. It is not necessary to remove any residual Microlyte® Matrix observed during secondary cover dressing changes. Please refer to the full instructions for use.

YOUR FIRST CHOICE IN WOUND CARE

The advanced materials science employed in Microlyte® enable a one of a kind wound matrix that is fully-synthetic, antimicrobial, and bioresorbable. That’s why Microlyte® is trusted for surgical and non-surgical wounds at inpatient and outpatient facilities across the nation.

Product Microlyte® Promogran Prisma Matrix Aquacel Ag Hydrofiber Acticoat Flex
Manufacturer Imbed Biosciences Systagenix (J&J) Convatec (BMS) Smith & Nephew
Composition Synthetic polymer Bovine collagen / regenerated cellulose Carboxymethyl cellulose Nylon fiber
Bioresorbable YES YES NO NO
Cell invasion /capillary ingrowth YES YES NO NO
Silver content (mg/100cm2) 1.2 mg 16.5 mg 12 mg 161 mg
Risk of tissue toxicity Low Minimal Minimal High
Easy to use Peel and place Need hydration Need hydration Need hydration
Painful removal NO NO YES YES
Price $$ $$ $ $

PUBLISHED RESEARCH ARTICLES

  • Interfacial stacks of polymeric nano films on soft biological surfaces that release multiple agents, ACS Applied Materials and Interfaces, 8, 26541-26551, 2016. M Herron, MJ Schurr, CJ Murphy, JF McAnulty, CJ Czuprynski, and NL Abbott.

  • Gallium-loaded dissolvable microfilm constructs that provide sustained release of Ga3+ for management of biofilms, Advanced Healthcare Materials, 4, 2849-2859, 2015. M Herron, MJ Schurr, CJ Murphy, JF McAnulty, CJ Czuprynski, and NL Abbott.
  • Reduction in wound bioburden using a silver-loaded dissolvable microfilm construct, Advanced Healthcare Materials, 3(6), 916-928, 2014. M Herron, A Agarwal, PR Kierski, DF Calderon, LBC Teixeira, MJ Schurr, CJ Murphy, CJ Czuprynski, JF McAnulty and NL Abbott.

  • Integration of silver nanoparticle-impregnated polyelectrolyte multilayers into murine splinted cutaneous wound beds, Journal of Burn Care and Research, 34(6), e359-367, 2013. KM Guthrie, A Agarwal, LBC Teixeira, RR Dubielzig, NL Abbott, CJ Murphy, H Singh, JF McAnulty and MJ Schurr.

  • Polymeric multilayers that localize the release of chlorhexidine from biologic wound dressings, Biomaterials, 33 (28), 6783-92, 2012. A Agarwal, TB Nelson, PR Kierski, MJ Schurr, CJ Murphy, CJ Czuprynski, JF McAnulty and NL Abbott.

  • Antibacterial efficacy of silver-impregnated polyelectrolyte multilayers immobilized on a biological dressing in a murine wound infection model, Annals of Surgery, 256 (2), 371-377, 2012. KMGuthrie, A Agarwal, DS Tackes, KW Johnson, NL Abbott, CJ Murphy, CJ Czuprynski, PR Kierski, MJ Schurr and JF McAnulty.

  • Polymeric multilayers that contain silver nanoparticles can be stamped onto biological tissues to provide antibacterial activity, Advanced Functional Materials, 21 (10), 1863-73, 2011. A Agarwal, KM Guthrie, MJ Schurr, CJ Czuprynski, JF McAnulty, CJ Murphy and NL Abbott.

  • Surfaces modified with nanometer thick silver-impregnated polymeric films that kill bacteria but support growth of mammalian cells, Biomaterials, 31 (4), 680-690, 2010. A Agarwal, TL Weis, MJ Schurr, NG Faith, CJ Czuprynski, JF Mcanulty, CJ Murphy and NL Abbott.

  • Book Chapter: Polymeric materials for chronic wound and burn dressings. Advanced Wound Repair Therapies. Farrar D, editor. Cambridge, UK: Woodhead Publishing Limited; 2011. Chapter 8; p.186-208; 649p. A Agarwal, JF McAnulty, MJ Schurr, CJ Murphy and NL Abbott.

PUBLISHED ABSTRACTS & CONFERENCE PROCEEDINGS

  • Microfilm wound contact dressing with metallic silver that conforms to wound-bed, prevents wound infection, and allows normal healing, 28th Annual Meeting of Wound Healing Society (WHS), Atlanta, GA. [Wound Repair Regeneration, 24(2), A1, 2016]. A Agarwal, G Pranami, TB Nelson, PR Kierski, DF Calderon, MJ Schurr, CJ Czuprynski, JF Mcanulty
  • Anti-Biofilm Efficacy of Novel Wound Dressings Containing Tryptophan, 28th Annual Meeting of Wound Healing Society (WHS), Atlanta, GA. [Wound Repair Regeneration, 23(2), A17, 2015]. KS Brandenburg, MB Herron, DF Calderon, PR Kierski, ET Watson, HL McAnulty, A Agarwal, NL Abbott, JF McAnulty, CJ Czuprynski
  • Transparent microfilm dressing with metallic silver particles prevents wound infection and allows normal wound healing, 24th Annual Meeting of Wound Healing Society (WHS), Orlando, FL. [Wound Repair Regeneration, 22(2), A27, 2014]. A Agarwal, TB Nelson, PR Kierski, DF Calderon, CJ Murphy, MJ Schurr, NL Abbott, CJ Czuprynski and JF McAnulty
  • Dissolvable microfilm dressing with silver-nanoparticles expedites healing of contaminated excisional wounds in mice, 23rd Annual Meeting of Wound Healing Society (WHS), Denver, CO. [Wound Repair Regeneration, 21(2), A13, 2013]. A Agarwal, TB Nelson, PR Kierski, M Budianto, CJ Murphy, MJ Schurr, CJ Czuprynski, NL Abbott and JF McAnulty
  • Antibacterial microfilm dressing with silver-nanoparticles promotes healing of contaminated excisional wounds, Annual Meeting of Society for Biomaterials (SFB), Boston, MA, 2013. A Agarwal, TB Nelson, PR Kierski, M Budianto, CJ Murphy, MJ Schurr, CJ Czuprynski, NL Abbott and JF McAnulty
  • Transferrable antibacterial nanofilms of silver-nanoparticles for artificial skin, 22nd Annual Meeting of Wound Healing Society (WHS), Atlanta, GA. [Wound Repair Regeneration, 20(2), A12, 2012. A Agarwal, M Budianto, AR Clarke, DS Tackes, MJ Schurr, CJ Murphy, CJ Czuprynski, JF McAnulty and NL Abbott
  • Biologic dressing stamped with a chlorhexidine-impregnated polymer film prevents infection and promotes normal healing in a murine wound-model, 22nd Annual Meeting of Wound Healing Society (WHS), Atlanta, GA. [Wound Repair Regeneration, 20(2), A12, 2012]. A Agarwal, TB Nelson, DS Tackes, AR Clarke, MJ Schurr, CJ Murphy, CJ Czuprynski, JF McAnulty and NL Abbott
  • Antibacterial molecular coatings of silver-nanoparticles for integration in wound-beds, 21st Annual Meeting of Wound Healing Society (WHS), Dallas, TX. [Wound Repair Regeneration, 19(2), A9, 2011]. A Agarwal, KM Guthrie, CJ Czuprynski, MJ Schurr, JF McAnulty, CJ Murphy and NL Abbott

  • Antibacterial efficacy of silver-impregnated polyelectrolyte multilayers immobilized on Biobrane in a murine wound infection model, 21st Annual Meeting of Wound Healing Society (WHS), Dallas, TX. [Wound Repair Regeneration, 19(2), A25, 2011]. KM Guthrie, A Agarwal, DS Tackes, KW Johnson, NL Abbott, CJ Muprhy, CJ Czuprynski, MJ Schurr and JF McAnulty

  • Integration of silver-impregnated polymeric multilayers onto biological tissues to provide antibacterial activity,Society for Biomaterials (SFB) Annual Meeting, Orlando, FL. [Poster] 2011. A Agarwal, KM Guthrie, CJ Czuprynski, MJ Schurr, JF McAnulty, CJ Murphy and NL Abbott
  • Effect of polyelectrolyte multilayer assembly on accessibility of immobilized growth factor, Society for Biomaterials (SFB) Annual Meeting, Orlando, FL.[Poster] 2011. N Shah, F Gorouhi, BL Wood, A Agarwal, J Covert, NL Abbott, R Isseroff and CJ Murphy
  • Mechanical transfer of silver into wound beds utilizing nanometer-thick polymer films that do not impair wound healing, American College of Veterinary Surgeons (ACVS) Veterinary Symposium, Seattle, WA. 2010. H Singh, A Agarwal, KM Guthrie, CJ Czuprynski, MJ Schurr, CJ Murphy, NL Abbott, JF McAnulty
  • Silver impregnated nanometer thick polymer films stamped on wound beds do not impair healing, 20th Annual Meeting of Wound Healing Society (WHS), Orlando, FL. [Poster]. [Wound Repair Regeneration 18(2), A44, 2010]. A Agarwal, KM Guthrie, H Singh, CJ Czuprynski, MJ Schurr, CJ Murphy, JF McAnulty and NL Abbott

  • Nanoscopically thin polymer films with silver nanoparticles that kill bacteria with but support growth of fibroblasts, 238th American Chemical Society (ACS) National Meeting, Washington, DC. [Polymeric Materials Science & Engineering Proceedings 101, 1450, 2009]. A Agarwal, TL Weis, MJ Schurr, NG Faith, CJ Czuprynski, JF McAnulty, CJ Murphy and NL Abbott
  • A novel, localized- release silver delivery system for chronic wounds, 19th Annual Meeting of Wound Healing Society (WHS), Dallas, TX. [Poster][Wound Repair Regeneration 17(2), A42, 2009]. A Agarwal, TL Weis, MJ Schurr, JF McAnulty, CJ Murphy and NL Abbott